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熱搜關鍵詞:拉曼光譜儀,光纖光譜儀,熒光光譜儀,地物光譜儀 | 
當前位置:技術支持 > 原位拉曼光譜儀-制藥反應的“智能眼” 技術文章

原位拉曼光譜儀-制藥反應的“智能眼”

點擊次數(shù):207  更新時間:2025-08-28

在制藥車間里,每一次化學反應都關乎藥品的質量與安全。如何實時掌握反應進程?如何避免高?;瘜W品的直接接觸?如何快速優(yōu)化工藝參數(shù)?

ATR7010原位反應過程拉曼光譜儀,正是制藥企業(yè)的“智能監(jiān)測助手"!它無需取樣、無需破壞樣品,實時捕捉分子振動信號,讓研發(fā)和生產全程透明可控!



核心優(yōu)勢

                ADVANTAGE              
7010主機.jpg
01

實時監(jiān)測

痛點:傳統(tǒng)檢測需頻繁停機取樣,易引入污染或延誤工藝調整。

解決方案:探頭直接伸入反應釜,實時追蹤關鍵成分濃度變化(如原料轉化率、雜質積累)。設置閾值報警,自動提醒反應終點或異常狀態(tài),減少副產物生成。



實際應用場景
ATR7010 的實際應用場景.jpg
02

無損檢測

痛點:強腐蝕性、易燃易爆樣品的傳統(tǒng)檢測風險高。

解決方案:耐高溫(最高300℃)、耐腐蝕(316L不銹鋼+哈氏合金探頭)設計,可直接接觸危險介質。一鍵式操作,無需復雜防護裝備,保障人員安全。


     配套探頭    7010配套探頭.jpg

03
高靈敏度

痛點:痕量雜質或中間體難以捕捉。

解決方案:制冷型CCD探測器,檢測限低至0.1%,輕松識別多晶型、溶劑殘留等關鍵指標。支持SERS增強技術,靈敏度進一步提升,滿足嚴苛質檢需求。

原位反應過程拉曼光譜分析儀的功能結構.jpg
功能結構
04
靈活高效

適用場景:結晶過程:監(jiān)測晶型轉變(如無定形→結晶態(tài)),優(yōu)化藥物溶出率。

流動化學:實時反饋連續(xù)流反應的穩(wěn)定性,避免放大生產失敗。

生物催化:追蹤酶活性變化,提升綠色合成效率。

部署便捷:光纖探頭最長可達100米(定制),主機與反應釜異地分離,靈活適配實驗室與產線。


技術硬核


           TECHNOLOGY           
01
精準光譜分析

原理:通過拉曼散射效應,記錄分子振動“指紋",區(qū)分同分異構體(如頭孢菌素異構體)。

數(shù)據(jù)可視化:二維/三維濃度趨勢圖,直觀展示反應進程;

自動建模功能,一鍵生成工藝參數(shù)優(yōu)化建議。

配套軟件.jpg
02

多波長選擇,應對復雜樣品


型號激發(fā)光波長功率適用場景

ATR7010-785:785nm ≥500mW,深色樣品(如石墨烯)

ATR7010-1064:1064nm ≥500mW,熒光干擾強的生物樣品

03
極&致穩(wěn)定性

光譜漂移≤1cm?1(10-40℃),強度波動<±2%,確保長期監(jiān)測數(shù)據(jù)可靠性。

高精技術   優(yōu)質服務
MANUFACTURING EQUIPMENT

奧譜天成是國產拉曼光譜儀領&軍&品牌,具有手持式、便攜式、科研級、工業(yè)在線級全系列拉曼產品線,能夠為客戶提供全場景的應用解決方案。




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